Most Studied Genes in Nutrigenomics
Nutrigenomics, the study of how genes and dietary components interact, has identified several key genes that play crucial roles in nutrition and health. Here are the most studied genes in this emerging field:
- FTO (Fat Mass and Obesity-Associated Gene): Associated with obesity risk, FTO influences food intake and energy balance.
- APOE (Apolipoprotein E): Involved in lipid metabolism, it affects dietary fat absorption and cardiovascular health.
- MTTP (Microsomal Triglyceride Transfer Protein): Plays a role in dietary fat processing and overall lipid metabolism.
- INS (Insulin): Critical for glucose homeostasis, variations in this gene impact carbohydrate metabolism.
- LEP (Leptin): This gene regulates energy balance and body weight by influencing appetite and metabolism.
- MTHFR (Methylenetetrahydrofolate Reductase): Important in folate metabolism, it is linked to various diseases influenced by diet.
Understanding these genes can help tailor nutritional strategies to individual genetic profiles, enhancing health outcomes.