Is Liver Cancer Hereditary?
Liver cancer, particularly hepatocellular carcinoma (HCC), is not typically classified as a hereditary disease. However, certain hereditary conditions can increase the risk of developing liver cancer. The most notable of these is hereditary hemochromatosis, a condition that causes excessive iron accumulation in the body, leading to liver damage and potentially cancer. Other genetic syndromes, such as Alpha-1 Antitrypsin Deficiency and Wilson's Disease, can also contribute to liver function impairment and increase cancer risk.
While family history of liver cancer can suggest a higher risk, often the connection is indirect. Environmental factors, lifestyle choices, and chronic liver diseases (such as viral hepatitis and cirrhosis) are significant contributors to liver cancer development. Individuals with chronic liver conditions may inherit genetic predispositions that exacerbate their risk.
Regular medical check-ups and screenings for those with a family history of liver disease are essential to detect any potential issues early. Lifestyle modifications, including a healthy diet and avoiding alcohol, can effectively reduce the risk of liver complications and cancer.