What is the Gluten Challenge Test?
The Gluten Challenge Test is a medical procedure used to diagnose celiac disease, an autoimmune disorder triggered by the ingestion of gluten. This test involves a carefully monitored increase in gluten intake after a period of gluten elimination from the diet.
Procedure
Initially, patients follow a strict gluten-free diet for at least 6 weeks to minimize symptoms and allow the body to stabilize. Following this period, the patient reintroduces gluten into their diet, typically in the form of wheat, barley, or rye products.
Monitoring
During the gluten challenge, patients are monitored for any emergence of symptoms, such as abdominal pain, diarrhea, or fatigue. Blood tests are conducted before, during, and after the challenge to measure specific antibodies related to celiac disease, namely tissue transglutaminase (tTG) antibodies.
Importance
The Gluten Challenge Test is crucial for accurate diagnosis, as it helps differentiate celiac disease from gluten sensitivity or other gastrointestinal issues. A positive response to gluten, both in symptoms and antibody levels, confirms the diagnosis, allowing for appropriate dietary recommendations and management.
It’s essential for this test to be conducted under medical supervision to ensure safety and proper interpretation of results.